Studies on the mechanism of action of insecticides in insects. Inhibition of the Acetylcholinesterase activity.

Abstract

P,p’-DDT unhibits the cholinesterase enzyme in the head and thorax of house flies Musca domestica nebulo Fabricius, but in the abdomen there is practically no inhibition. In the whole fly DDT inhibits this enzyme gradually, showing ist maximum inhibition (89,3%) 24 hours of application. In the case of thoracic ganglia the anti-cholinesterase activity is very much pronounced, i.e. 56,7% and 86,4% after 2 and 24 hours respectively.